Saturday, February 3, 2018

Toxoplasmosis in Post Heart Transplant

Q: In which of the following, there is the highest incidence of Toxoplasmosis, post Solid Organ Transplants (SOT)?  

A) Kidney
B) Liver
C) Heart

D) Pancrease
E) Lung


Answer: C

Out of all, the post cardiac transplant patients have shown to have the highest incidence of toxoplasmosis. This may be due to the fact that parasitic cysts can reside in the myocardium. Often it occurs within 90 days of the transplantation and presents with mental status change (encephalopathy).  Hallmark of this disease with ring-enhancing lesions can be seen on MRI of the brain.


Reference:

Munoz P, Valerio M, Palomo J, et al. Infectious and non-infectious neurologic complications in heart transplant recipients. Medicine (Baltimore). 2010;89(3):166–175

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