Sunday, October 1, 2017

Q; What percentage of patients have neurological complications who require Extra Corporeal Membrane Oxygenation (ECMO) for pulmonary reason and cardiopulmonary reason respectively?


Answer:  As per  Extracorporeal Life Support Organization (ELSO) registry, the incidence of neurologic injury in adult respiratory failure (ARDS or ALI) patients is 10 percent but the incidence rise to 50 percent, if ECMO support is instituted  during cardiopulmonary resuscitation.

In pure pulmonary pathology, Veno-Venous (V-V ECMO) is required but in hemodynamic collapse Veno-Arterial (V-A ECMO) is required.


References: 

1. Brogan TV, Thiagarajan RR, Rycus PT, et al. Extracorporeal membrane oxygenation in adults with severe respiratory failure: a multi-center database. Intensive Care Med 2009; 35:2105.

2. Mateen FJ, Muralidharan R, Shinohara RT, et al. Neurological injury in adults treated with extracorporeal membrane oxygenation. Arch Neurol 2011; 68:1543.

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