Q: Within how many days the resolution of thrombocytopenia should be apparent following withdrawal of heparin in Heparin Induced Thrombocytopeni (HIT)?


Answer:  Within seven days

Though academically seven days are said for the resolution of thrombocytopenia following withdrawal of heparin in HIT patients but pragmatically a trend towards improving platelet count should start happening within three to four days - and if not suspicion for other causes or continue heparin exposure should be looked for.