Wednesday, October 5, 2016

Q: In factitious hypoglycemia caused by sulfonylureas or meglitinides ingestion 

A) Plasma Insulin will be high
B) Plasma insulin will be low
C) Plasma C-peptide will be low
D) Plasma proinsulin will be low


Answer: A

Factitious hypoglycemia from sulfonylureas or meglitinides is very hard to detect as they mimic like insulinoma as they work by stimulating insulin secretion. Levels of all three i.e plasma insulin, C-peptide, and proinsulin will be high. The most accurate test would be to directly measure plasma sulfonylureas or meglitinides. 

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