Q: Why cardiac workup is essential during diagnosis and management of Myxedema coma?

Answer: Cardiac workup, particularly ruling out myocardial infarction (MI) and cardiac ischemia, is essential during diagnosis and management of Myxedema coma for 2 reasons

1. It is not uncommon for myocardial ischemia/infarction to be  a precipitant of myxedema coma/crisis

2. Full-dose T4 therapy may worsen myocardial ischemia by increasing myocardial oxygen demand.