Q: What are the 2 major kinds of Dialysates used in CRRT?
1. Lactate based Dialysate solution
2. 8.4% bicarbonate based dialysate
Lactate is commonly used as buffer. In conditions where inadequate lactate metabolism takes place (eg. in liver failure) the bicarbonate based dialysate is preferred. However, recent studies suggest that bicarbonate-buffered replacement fluids can improve acid-base status and reduce cardiovascular events better than lactate fluids. Both fluids should contain electrolytes in concentrations aiming for a physiologic level and taking into account preexisting deficits or excess and all input and losses.