Thursday, April 10, 2014

Q: Which benzodiazepine is more prone to have paradoxical effects than any other benzodiazepines?


Answer: Lorazepam

Paradoxical effects of benzodiazepines like increased hostility, aggression, angry outbursts, and psychomotor agitation are seen more commonly with lorazepam than any other benzodiazepines.



Reference:

Sorel L, Mechler L, Harmant J (1981). "Comparative trial of intravenous lorazepam and clonazepam im status epilepticus". Clinical Therapeutics 4 (4): 326–336

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