Wednesday, January 15, 2014

Q: Name 5 drugs which can be use for post-operative shivering?


Answer: 

There is no pharmacological treatment  "Gold standard"  identified for post-operative shivering. Following drugs have been used with various success, meperidine been most responsive.

1. Meperidine
2. Tramadol
3. Magnesium
4. Clonidine
5. Dexmedetomidine



References:

1. Kranke P, Eberhart LH, Roewer N, Tramer MR. Pharmacological treatment of postoperative shivering: a quantitative systematic review of randomized controlled trials. Anesth Analg. 2002;949(2):453-460.

2. Kranke P, Eberhart LH, Roewer N, Tramer MR. Single-dose parenteral pharmacological interventions for the prevention of postoperative shivering: a quantitative systematic review of randomized controlled trials. Anesth Analg. 2004; 99(3):718-727.

3. Schwarzkopf KRG, Hoff H, Hartmann M, Fritz HG. A comparison between meperidine, clonidine, and urapidil in the treatment of postanesthetic shivering. Anesth Analg. 2001;92(1):257-260.

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