Q: What could be the 4 life threatening side effects of Neupogen (Filgrastim)?
1. Neupogen may bring sickle cell crisis after receiving it in patients with sickle cell disorders.
2. Spleen Rupture has been reported after the administration of Neupogen. Patients receiving Neupogen who report left upper abdominal pain should be evaluated for it.
3. ARDs (Acute respiratory distress syndrome) has been reported secondary to an influx of neutrophils to sites of inflammation in the lungs.
4. Alveolar Hemorrhage and Hemoptysis.