Thursday, November 3, 2011

Q: Caspofungin may cause which electrolyte abnormality?
Answer: Hypokalemia
Beside increase liver enzymes, other rare but life threatening side effects reported so far includes severe thrombophlebitis (require a greater dilution and infusion over an extended period) and severe hypokalemia, with serum potassium levels as low as 1.7 mg/dl.
Experience with Caspofungin in the Treatment of Persistent Fungemia in Neonates - Journal of Perinatology (2005) 25, 770–777; published online 13 October 2005

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